Endocrine Abstracts

Pheochromocytomas and paragangliomas are rare but life threatening tumors secreting catecholamines. They could be either sporadic or inherited. Either isolated or integrated in genetic syndromes such as Von Hippel Lindau (VHL) (OMIM193300) which is an autosomal dominant disorder resulting from germline mutations in the VHL gene.Observation: We report a 42-year-old man operated at 8 years old for bilateral pheochromocytoma revealed by adrenergic symptoms ...

Introduction: Cortisol has numerous actions on glucose metabolism and insulin action which explain the frequency of glucose abnormalities in Cushing’s syndrome (CS). The aim of our work was to assess the prevalence and characteristics of diabetes in CS.Material and methods: This is a retrospective study concerning 51 CS (44F/7M) in whom we looked for the presence of diabetes either by fasting glycaemia or 75 g oral glucose tolerance test. Thereafter...

Introduction: Cortisol activates lipolysis in adipose tissue resulting in the release of free fatty acids into the circulation, it also activates cholesterol and triglycerides synthesis. The consequence is an increase in total circulating cholesterol and triglycerides with their inherent risks on the cardiovascular system. The aim of our work was to assess the prevalence and characteristics of dyslipidaemia in Cushing’s syndrome (CS).Material and me...

Introduction: Patients with Cushing’s syndrome (CS) are prone to hypertension as cortisol stimulates renal reabsorption of sodium and enhances vascular sensitivity to catecholamine and angiotensin II. This explains the frequency of hypertension in patients with CS. The aim of our work was to assess the prevalence and characteristics of hypertension in CS.Material and methods: This is a retrospective study concerning 51 CS (44F/7M) in whom we looked ...

Introduction: Pituitary apoplexy is a rare endocrine emergency characterized by the sudden onset of severe headaches, vomiting, visual abnormalities and pituitary dysfunction secondary to an acute hemorrhage or infarction within a pituitary adenoma.Subjects and methods: We report a retrospective study from 2000 to 2014 of 23 cases with pituitary apoplexy. Their mean age was 38.7±14.8 years, with a male to female ratio of 2:1.R...

Introduction: Pituitary apoplexy is a rare endocrine emergency characterized by the sudden onset of severe headaches, vomiting, visual abnormalities and pituitary dysfunction secondary to an acute hemorrhage or infarction within a pituitary adenoma.Subjects and methods: We report a retrospective study from 2000 to 2014 of 23 cases with pituitary apoplexy. Their mean age was 38.7 years ±10 years, with a male to female ratio of 2:1. All patients benef...